| Scheduled | Played | Round | Home Team | Away Team | |
|---|---|---|---|---|---|
| 2021-11-25 | 2021-11-25 | 1 | Over CCC | 4 - 5 | Fulbourn S.S.C. (IDA) |
| 2021-11-25 | 2021-11-25 | 1 | Plough (A) | 6 - 3 | Dobblers (A) |
| 2021-11-25 | 2021-11-25 | 1 | Milton (C) | 3 - 6 | Bell Inn (Balsham) |
| 2021-11-25 | 2021-11-25 | 1 | Girton S.C. (A) | 8 - 1 | Chesterton WMC (Ship B) |
| 2021-11-25 | 2021-11-25 | 1 | Chestnut Tree | 4 - 5 | Newton S.S.C. (A) |
| 2021-11-25 | 2021-11-25 | 1 | Whittlesford S.S.C. | 3 - 6 | C U Old Skool |
| 2021-11-25 | 2021-11-25 | 1 | Pavilion | 3 - 6 | Hardwick S.S.C. (B) |
| 2021-11-25 | 2021-11-25 | 1 | Carlton Arms | 5 - 0 | Milton (B) |
| 2021-11-25 | 2021-11-25 | 1 | Dobblers (B) | 7 - 2 | King Street Run (X) |
| 2021-11-25 | 2021-11-25 | 1 | Milton (A) | 7 - 2 | Salisbury Club (B) |
| 2021-11-25 | 2021-11-25 | 1 | White Lion (Exiles) | 5 - 4 | Rathmore (Q) |
| 2021-11-25 | 2021-11-25 | 1 | Hardwick S.S.C. (A) | 6 - 3 | NCI Moonshine |
| 2021-11-25 | 2021-11-25 | 1 | Milton Arms (Ship A) | 4 - 5 | Histon R.B.L. (Z) |
| 2021-11-25 | 2021-11-25 | 1 | Tev Xcons | 8 - 1 | Fulbourn Institute (Amber) |
| 2021-11-25 | 2021-11-25 | 1 | Newton S.S.C. (B) | 5 - 4 | White Horse (A) (Swavesey) |
| 2021-12-09 | 2021-12-09 | 2 | Tev Xcons | 7 - 2 | Girton S.C. (A) |
| 2021-12-09 | 2021-12-09 | 2 | Fulbourn S.S.C. (IDA) | 6 - 3 | Histon R.B.L. (Z) |
| 2021-12-09 | 2021-12-09 | 2 | Carlton Arms | 5 - 0 | Milton (A) |
| 2021-12-09 | 2021-12-09 | 2 | C U Old Skool | 5 - 4 | Hardwick S.S.C. (A) |
| 2021-12-09 | 2021-12-09 | 2 | Newton S.S.C. (A) | 6 - 3 | White Lion (Exiles) |
| 2021-12-09 | 2021-12-09 | 2 | Hardwick S.S.C. (B) | 2 - 7 | Plough (A) |
| 2021-12-09 | 2021-12-09 | 2 | Fulbourn Institute Misfits | 6 - 3 | Newton S.S.C. (B) |
| 2021-12-09 | 2021-12-09 | 2 | Bell Inn (Balsham) | 5 - 4 | Dobblers (B) |
| 2022-01-23 | 2022-01-23 | 3 | Carlton Arms | 6 - 3 | Fulbourn S.S.C. (IDA) |
| 2022-01-23 | 2022-01-23 | 3 | Plough (A) | 4 - 5 | Tev Xcons |
| 2022-01-23 | 2022-01-23 | 3 | Fulbourn Institute Misfits | 5 - 4 | C U Old Skool |
| 2022-01-23 | 2022-01-23 | 3 | Bell Inn (Balsham) | 1 - 8 | Newton S.S.C. (A) |